Question: I frequently deal with a stuffy nose and rely on nasal drops or spray for relief. How long is it safe to use nasal spray? I heard it shouldn't exceed a week, but I often use it longer. Could I be addicted? — P.K., Geffen
Pharmacist Marjan Terpstra responds: Nasal drops or sprays containing xylometazoline are meant for short-term use only—not longer than one week. These decongestants work by shrinking swollen nasal mucosa. When you have a stuffy nose, inflammation causes blood vessels in the nasal lining to dilate. Xylometazoline constricts them, reducing fluid buildup and swelling, which clears the blockage and improves breathing.
Our nasal passages are lined with cilia—tiny hair-like structures that protect against dust, regulate temperature, and help with smell. Xylometazoline reduces blood flow to the nasal surface, limiting oxygen to these cilia. Prolonged use, even just beyond a week, can damage or kill them.
Moreover, blood vessels can develop tolerance to xylometazoline, requiring higher doses for the same effect, which is harmful and addictive. The solution? Stop using it immediately.
Switch to saline nasal drops instead—a gentle, safe option with fewer risks. Pregnant women should avoid xylometazoline sprays entirely, as some active ingredient may enter the bloodstream and affect placental blood flow. Always consult a pharmacist or doctor before using over-the-counter nasal products for personalized advice.
