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Why people gain weight as they get older

Many people struggle to control their weight as they age. New research has now shown why that is:Fat turnover in adipose tissue decreases with age and makes it easier to gain weight, even if we don't eat more or exercise less than before.

The scientists studied the fat cells in 54 men and women over an average period of 13 years. During that time, all subjects, whether gaining or losing weight, showed a decrease in lipid turnover in the adipose tissue, that is, the rate at which lipids (or fat) are removed and stored in the fat cells. Those who did not compensate by eating fewer calories gained an average of 20 percent.

The researchers also examined lipid turnover in 41 women undergoing bariatric surgery and how lipid turnover affected their ability to keep the weight off four to seven years after surgery. The result showed that only those who had a low percentage before surgery managed to increase their lipid turnover and maintain their weight loss. The researchers think these people may have had more leeway to increase their lipid turnover than those who already had high-level pre-surgery.

Previous studies have shown that one way to accelerate fat turnover in adipose tissue is to exercise more. This new research supports that idea and further indicates that the long-term outcome of weight loss surgery would improve when combined with increased physical activity.