Dreading the dentist? You might soon overcome that fear. Researchers have uncovered a way for teeth to naturally repair cavities.
Evidence shows that Tideglusib—a drug typically prescribed for Alzheimer's disease—triggers the growth of new dentin, the protective layer beneath the tooth's enamel. While teeth produce a thin dentin layer during infections, it's often inadequate against deep decay.
In lab tests, scientists applied Tideglusib to a tiny collagen sponge and placed it in the cavity. The tooth regenerated dentin to fill the hole, and the sponge dissolved naturally. With Tideglusib already tested for safety in Alzheimer's trials, this approach could reach clinics faster. For now, though, dental drills remain essential.